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Rodriguez-Iturbe B, Pons H, Johnson RJ

Patients have described feeling cold in different ways

The newly synthesized p62 protein further binds to and inhibits Keap1, thereby amplifying the NRF2 signaling pathway ( Activation of the NRF2 pathway effectively suppresses intestinal ferroptosis

Tanaka S, Tanaka S, Iimuro S, Yamashita H, Katayama S, Akanuma Y, Yamada N, Araki A, Ito H, Sone H, Ohashi Y, Japan Diabetes Complications Study Group